Revolutionary Study Unveils Eye-Opening Connection

A groundbreaking study presented at the European Academy of Dermatology and Venereology Congress 2025 has revealed a startling link between psoriasis and age-related macular degeneration (AMD) that could change how we view skin and eye health.

This extensive research, the first of its kind, uncovers that individuals suffering from psoriasis face a significantly heightened risk of developing AMD, especially the dry form that can lead to progressive vision loss.

What the Research Showed: Disturbing Findings

Conducted as a nationwide cohort study beginning in January 2025, this analysis examined over 2 million patients, specifically focusing on those diagnosed with type 2 diabetes. It unearthed alarming statistics: psoriasis patients were found to have a far greater likelihood of suffering from AMD compared to their psoriasis-free counterparts.

Dr. Alison Treichel, from the University of Rochester Medical Center, stated, "Given that abnormal lipid deposits in the retina are a key feature of AMD, it makes biological sense that psoriasis, characterized by similar issues, could elevate this risk."

Comprehensive Study Methodology: Numbers Don't Lie

The research analyzed data from 22,901 psoriasis patients aged 55 and older, all of whom had undergone an eye exam within the last decade. To ensure robust comparisons, participants were matched against three control groups, including those with melanocytic nevi and major depressive disorder.

The 10-year incidence and risk ratios of different AMD types were meticulously assessed, revealing a staggering association between psoriasis and unspecified AMD. The results turned heads, with risk ratios indicating a significantly increased likelihood of AMD for those with psoriasis.

Treatment Insights: Do Biologics Hold the Key?

In a separate evaluation, researchers looked at psoriasis patients treated with biologics versus those using topical corticosteroids. The findings were promising: the biologic group exhibited a 27% lower risk of developing AMD compared to those relying solely on corticosteroids.

Looking Ahead: Implications for Future Research

Dr. Treichel emphasized the potential shared mechanisms between psoriasis and AMD, suggesting that further studies are essential to explore this association comprehensively. These findings not only hint at the protective benefits of biologic therapies beyond skin issues but also underscore the importance of lifestyle factors like smoking and obesity on ocular health.

As this research unfolds, it paves the way for deeper investigations that could potentially revolutionize both psoriasis treatment and preventative strategies for eye diseases.