Keto Diet Raises Eyebrows in New Mouse Study

Popular for its promise of quick weight loss, the ketogenic diet is now facing scrutiny in light of a long-term study that could reshape our understanding of its implications for health. This high-fat, low-carb diet has been a go-to for managing obesity and diabetes, but new findings suggest it may come with serious risks.

What Did the Study Find?

Research published in *Science Advances* shows that mice fed a ketogenic diet for nearly a year experienced worrying increases in blood lipids and liver fat, alongside impaired glucose regulation. Alarmingly, while weight loss occurred, significant metabolic health problems emerged.

The Dark Side of Keto: High Cholesterol and Fatty Liver Disease

The study revealed that these mice exhibited elevated plasma lipid levels and signs of fatty liver disease, a serious condition characterized by excessive fat buildup in the liver. Notably, the female mice did not show similar liver issues, prompting further questions about gender differences in dietary impacts.

Insulin Woes: The Hidden Metabolic Toll of Keto

Perhaps more concerning, the keto diet resulted in impaired insulin secretion, which is crucial for blood sugar regulation. While some mice showed improved glucose tolerance within weeks of switching to a low-fat diet, those on keto struggled to manage their blood sugar effectively.

A Cautionary Tale for Diet Enthusiasts

Dr. Amandine Chaix, one of the study’s authors, stresses that these findings warrant caution. The quick weight loss attributed to the keto diet is not a free pass for long-term consumption, especially for those with pre-existing conditions like obesity or diabetes. She advocates for more research in humans to understand the potential cardiometabolic risks tied to prolonged ketogenic dieting.

What's Next for Keto Dieters?

Despite its allure, these new insights serve as a crucial reminder: just because a diet promotes weight loss doesn’t mean it’s safe or effective long-term. For those considering the keto lifestyle, it may be wise to consult healthcare professionals and explore balanced dietary options that promote both weight loss and overall health.