As the college football season heats up, Week 5 presents some exciting matchups and potential surprises.

The reigning national champion Michigan Wolverines made a significant leap up the rankings, moving to No. 12 after a nail-biting 27-24 victory against No. 11 USC. Despite suffering an early-season setback against an unexpected opponent, they are back on track, now favored by 10 points at home against Minnesota.

This week is pivotal, featuring top-tier clashes including No. 2 Georgia facing No. 4 Alabama, and No. 9 Penn State hosting No. 19 Illinois. Fans and bettors alike are closely analyzing these games, but before placing your bets, it’s essential to check out the predictions from SportsLine's advanced model—a system that has generated over $2,000 in profits for its players since its inception!

Top Predictions for an Action-Packed Week 5

One highlight from the model is its confidence in No. 16 Notre Dame, who is predicted to secure a decisive victory over No. 15 Louisville, with a spread of 6.5 points. After a less-than-stellar performance earlier in the season, the Fighting Irish rebounded with an impressive 28-3 win against Miami (Ohio). If Notre Dame wants a shot at the College Football Playoff, they must demonstrate dominance in their upcoming games.

The Fighting Irish, who were initially ranked No. 7 in the preseason due to their formidable defense, currently rank seventh in scoring defense, allowing just 9.8 points per game. Their pass defense has been remarkable, and they ranked second nationally in completion percentage allowed. The model predicts Notre Dame will cover the spread in nearly 60% of its simulations, showcasing their strong position heading into this match.

On another note, No. 21 Oklahoma, fresh off an SEC debut defeat against Tennessee, is expected to bounce back with a win against Auburn. Despite last week's loss, quarterback Michael Hawkins Jr. showed promise, leading the Sooners with a pair of late-game scoring drives. Conversely, Auburn's recent performance has been underwhelming, and this gives the Sooners an edge, as the model suggests they will cover the spread in over 60% of simulations.

Get Ready for Upsets!

Excitement builds as the model has also predicted that ten underdogs will win outright in Week 5, including an unexpected upset in one of the week’s marquee matchups. To stay ahead of the game and make informed bets, don't miss out on the detailed odds and predictions provided by SportsLine.

Upcoming Matchups & Odds for Week 5

Here are the key matchups to keep an eye on as the weekend approaches:

Virginia Tech at Miami (-17.5, 54.5)

Washington at Rutgers (-1.5, 44.5)

Minnesota at Michigan (-10, 35.5)

Louisville at Notre Dame (-6.5, 46)

Oklahoma at Auburn (+1, 45)

Georgia at Alabama (+1, 49.5)

As college football’s drama unfolds this weekend, make sure you know all the odds and predictions, keeping an eye on the potential for big wins and thrilling upsets! Stay tuned for more updates and insights as we dissect each matchup leading up to game day.