New Variant Alert: NB.1.8.1 on the Rise!

In May 2025, the new COVID-19 variant NB.1.8.1 has captured global attention as it emerges as a subvariant of the Omicron lineage JN.1. This variant is already causing a surge in cases across Asia and has made its way into the United States. With health authorities keeping a close watch, it’s crucial to understand the implications of this variant!

What is NB.1.8.1?

First detected in China, NB.1.8.1 quickly became the dominant strain there, leading to a significant rise in COVID-19 infections. It has now also been confirmed in multiple Asian countries, including Singapore and Hong Kong, and is turning up in U.S. airport screenings, raising eyebrows among health experts.

WHO’s Take on This Variant

The World Health Organization (WHO) has labeled NB.1.8.1 as a variant under monitoring (VUM) due to its increasing global presence. According to their report, this strain is a derivative of the recombinant variant XDV.1.5.1, with the earliest sample collected on January 22, 2025. This variant is one of six VUMs currently being tracked by the WHO.

Symptoms: What You Should Watch For!

Symptoms associated with NB.1.8.1 closely mirror those of earlier Omicron variants. Commonly reported symptoms include:

- Sore throat - Fatigue - Mild cough - Fever - Muscle aches - Congestion Some patients have reported experiencing low-grade hyperthermia, which is an unusual elevation in body temperature. Other symptoms may include headaches, nausea, loss of appetite, and gastrointestinal issues.

Is This Variant More Contagious?

NB.1.8.1 shows a higher transmissibility rate compared to earlier variants. Preliminary findings suggest that it may bind more effectively to human cells, leading to increased infection potential. Major U.S. airports—such as those in California, Washington, Virginia, and New York—are now screening for this variant, further emphasizing the need for surveillance and public health measures.

No Need to Panic, But Stay Vigilant!

While there is a rise in cases and hospitalizations in regions with widespread NB.1.8.1 cases, the WHO reports that current data does not indicate that this variant causes more severe illness than those currently circulating.

Expert Opinion: Trends in India

In India, a mild uptick in COVID-19 cases is seen, primarily driven by the emergence of new Omicron subvariants like JN.1. Dr. Divya K S, a Consultant Infectious Disease Specialist, notes that as infections become endemic, periodic surges are expected. However, the current situation is not alarming, with most cases being mild and presenting common symptoms like fever and fatigue. Still, it’s better to remain vigilant, especially for vulnerable populations.