March Madness 2025: Expert Predictions for the Sweet 16 as Brackets Crumble

As we advance into the Sweet 16 of the 2025 NCAA Tournament, the drama has been palpable. Notably, all four No. 1 seeds have successfully navigated the first two rounds, but shockingly, only one double-digit seed—preseason dark horse No. 16 Arkansas, now a No. 10 seed—continues to defy the odds. What’s the situation? Every single bracket at CBS Sports has been shattered, including those of our so-called 'experts.'

With that in mind, we decided to reset our predictions and take a closer look at the Sweet 16 matchups. Prepare for surprises as we analyze who might emerge triumphant in this chaotic yet thrilling tournament.

Gary Parrish, College Basketball Insider:

- Original Champion Pick: Auburn While I'm hesitant to adjust my championship pick of Auburn, I must confess they've struggled recently, hovering at a .500 record in their last six games. Despite these setbacks, I still believe in their potential resurgence. They were once hailed as the best team this season, and there's no reason their talent can't shine again. I’m sticking with them to conquer Houston in the championship game.

Matt Norlander, Senior Writer:

- Original Champion Pick: Houston Despite losing my Final Four pick of St. John's, I am still in good shape with my remaining selections. However, it’s time for a strategic pivot out West—Texas Tech will make it to the Final Four. Their advanced stats are impressive, boasting a top-five offense led by All-American JT Toppin. For my championship choice, I'm sticking with Houston, as they have displayed remarkable depth and skill throughout the tournament.

Dennis Dodd, Senior Writer:

- Original Champion Pick: Houston Houston has proven their resilience through both offense and defense, which will serve them well as they approach the Sweet 16. Despite a slight defensive hiccup against Gonzaga, their multi-faceted attack—with standout backcourt players LJ Cryer and Milos Uzan—sets them apart from the competition. The Cougars are poised for a strong finish.

Kyle Boone, College Basketball Writer:

- Original Champion Pick: Duke Duke continues their path of dominance, showcasing incredible depth and talent this season. Their expected showdown against Auburn promises to be a nail-biter. I’m banking on the Blue Devils to clinch the title by overpowering the Tigers, securing their legacy as one of the season’s best teams.

David Cobb, College Basketball Writer:

- Original Champion Pick: Florida Despite a tense match against UConn, Florida's guard play remains unmatched, making them a formidable contender. Led by coach Todd Golden, they have prevailed over tough competition, and their experience could be the secret ingredient in their pursuit of the championship.

Cameron Salerno, College Basketball Writer:

- Original Champion Pick: Duke Given Duke’s remarkable performance, I remain steadfast in my prediction. The Blue Devils seem on a collision course with Florida for the national title, and their synergy on the court is a sight to behold.

Chip Patterson, College Basketball Writer:

- Original Champion Pick: Duke With my Final Four picks intact, I feel even more confident in Duke's trajectory. They have demonstrated consistent dominance throughout the tournament, reminiscent of historical greats. Tyrese Proctor and Cooper Flagg are hitting their stride, making them an unstoppable force.

Jerry Palm, Bracketology Expert:

- Original Champion Pick: Florida Despite a challenging game against UConn, the Gators remain my pick. Known for their robust guard play and bracket dominance, they have proven themselves as a powerhouse within the tournament this season.

Isaac Trotter, College Basketball Writer:

- Original Champion Pick: Duke My faith in Duke continues to grow, as they seemed destined for a championship run. Their current form demonstrates that they are capable of cutting down the nets in San Antonio, solidifying a monumental season.

As we dive deeper into March Madness, it remains anyone's guess who will emerge victorious. Buckle up, because the Sweet 16 is just getting started—and surprises are on the horizon!