
Significant Progress in Closing Gender Gap in Heart Disease Outcomes
2025-03-31
Author: Benjamin
Introduction
A groundbreaking study conducted by researchers at Intermountain Health has revealed that the disparities in heart disease outcomes between men and women are steadily diminishing. Heart disease remains the leading cause of mortality among women aged 20 and older, affecting approximately 45% of this demographic. However, this new research uncovers a promising trend: the gap in cardiac event prevalence between genders is narrowing.
Principal investigator Kismet Rasmusson, a nurse practitioner at Intermountain Health, stated, "The reality is that women are different from men and need to be evaluated, diagnosed, and treated differently for heart disease. While these findings show we’ve made progress, we still have a long way to go."
Study Overview and Methodology
The study analyzed data from 14,248 women and 26,524 men who underwent coronary angiography at Intermountain Health between 2000 and 2019. Coronary angiography utilizes X-rays and contrast dye to visualize the coronary arteries, which are crucial for blood flow to the heart and are indicative of increased heart attack risk when obstructed.
Data extracted from electronic health records showed that men were more likely to present with risk factors such as smoking, previous heart attacks, left ventricular dysfunction, and hyperlipidemia. Conversely, women tended to have additional health issues like diabetes, high blood pressure, and a history of strokes or heart failures. Interestingly, women typically experienced less severe chest pain upon arriving at the catheterization lab compared to men.
In terms of physiology, the results indicated that women had less arterial blockage and underwent significantly less revascularization procedures within 60 days. Additionally, men more commonly received coronary artery bypass grafts. Alarmingly, prescriptions for cardiac medications were more frequently given to men, despite evidence suggesting that such medications positively influence patient outcomes.
Long-Term Outcomes and Mortality
The study also discovered that women had a notably higher likelihood of suffering a major cardiac event within one to three years compared to their male counterparts, largely contributing to higher mortality rates among women. Nevertheless, as the data was segmented into five-year increments, it became evident that these disparities have been decreasing over time. By the period of 2015 to 2019, no significant differences in the rates of major cardiac events between women and men were observed—a promising indication of progress in cardiac care.
Rasmusson emphasized that the data highlights unique risk factors prevalent in women, aligning with findings from previous research studies.
Limitations and the Need for Risk Management
Despite the encouraging trends, researchers noted some limitations, pointing out that the findings may not represent national trends since the data was exclusively sourced from one healthcare system. Furthermore, awareness of heart disease risks has plunged over the years, dropping from 65% in 2009 to only 44% in 2019—leaving a substantial number of women uninformed about their vulnerability to heart disease.
A related study showcased at the American College of Cardiology’s Annual Scientific Session revealed that women with poor or intermediate heart health factors face a staggering five-fold increase in heart disease risk compared to men with similar health conditions.
Rasmusson cautioned, "Women need to understand that their risk of heart disease is equal to that of men and that it remains the leading cause of death, more so than all cancers combined. It is essential for women to manage their risk factors, recognize cardiac symptoms, and seek timely medical attention—this can truly make a difference in saving lives."
As awareness grows and healthcare becomes more tailored to women’s unique health needs, the path towards equitable heart disease outcomes is becoming clearer. The narrowing gender gap in heart disease is not only a medical victory but also a call to action for increased education and proactive health management among women globally.