In the fast-paced world of Fantasy Football, championships aren't just won at the draft table; they're secured through smart roster management all season long. Recognizing valuable players to add to your lineup after each NFL week is crucial. That's where I step in, bringing you the must-know pickups for Week 2!

Top Waiver Wire Picks for Week 2

Michael Penix Jr., QB, Falcons

Michael Penix Jr. exploded onto the scene in Week 1, launching 42 passes and racking up 298 yards with a touchdown, plus an impressive rushing performance that included a touchdown. With the Falcons' dynamic trio of Drake London, Bijan Robinson, and Kyle Pitts, Penix has immense potential for the upcoming weeks—fingers crossed that London’s injury isn’t severe!

Daniel Jones, QB, Colts

In his Colts debut, Daniel Jones dazzled with a 75.9% completion rate, throwing for 272 yards and scoring three touchdowns—29.48 Fantasy Points! His connection with Michael Pittman Jr. and rookie Tyler Warren signifies a flourishing offense. As a dual-threat quarterback, Jones offers serious upside—this system might be the perfect fit for him.

Hollywood Brown, WR, Chiefs

With Rashee Rice suspended, Hollywood Brown emerged as the primary target for Patrick Mahomes, snagging 10 catches on 16 targets for 99 yards in Week 1. This performance can’t be understated; Mahomes rarely lets such opportunities slip by. Brown's past as a first-round pick adds to his potential as a Fantasy asset.

Quentin Johnston, WR, Chargers

After a victorious outing against the Chiefs, Quentin Johnston shone brightly, catching two touchdowns and racking up 79 yards on five receptions. Despite sharing targets, his early performance indicates he could finally fulfill the high expectations placed on him since being a first-round pick.

Dylan Sampson, RB, Browns

Rookie Dylan Sampson turned heads in Week 1, out-touching Jerome Ford significantly. With 12 carries and 64 receiving yards, Sampson scored a solid 17.3 Fantasy Points. Keep an eye on him as he could become the go-to pass-catching back in Cleveland soon!

Harold Fannin Jr., TE, Browns

Rookie tight end Harold Fannin Jr. surprised many by leading the Browns in targets during Week 1, catching seven balls for 63 yards. Last season's stats show his potential—he dominated college football in receptions and yards. As a versatile receiver in a tight end's body, Fannin could find himself a weekly role.

Wan'Dale Robinson, WR, Giants

Despite a rough Fantasy season last year, Wan'Dale Robinson is showing promise in 2025. With six catches on eight targets for 55 yards in Week 1, he may not be a high-scoring player but his position as a reliable second option makes him a safe pick to fill your roster.

Kayshon Boutte, WR, Patriots

Kayshon Boutte started strong, catching six passes for 103 yards in Week 1, emerging as a key player in New England’s offense. With an undefined role in the receiving corps, he could maximize those opportunities for solid weekly production.

Cedric Tillman, WR, Browns

After a promising return from injury, Cedric Tillman caught five of his eight targets for 52 yards and a touchdown in Week 1. His ability to score makes him a solid FLEX option moving forward, potentially finding more opportunities alongside Jerry Jeudy.

Joshua Palmer, WR, Bills

Joshua Palmer kicked off the season impressively with five catches and 61 yards, partnering well with Josh Allen. As a big-play receiver, his connection to Allen suggests that exciting weeks are ahead!

Juwan Johnson, TE, Saints

Tight end Juwan Johnson secured 76 yards on eight receptions this past week, making him a dependable target in the Saints’ offense. With Rattler's passing volume poised to continue, Johnson could become a key piece for Fantasy managers.

Calvin Austin III, WR, Steelers

Calvin Austin III is gaining traction, catching four passes for 70 yards in a high-scoring opener. Tied for second in targets on a high-octane Steelers offense, his potential as a reliable WR2 makes him worth considering.

Ray-Ray McCloud III, WR, Falcons

Keep an eye on Ray-Ray McCloud, who caught three passes for 51 yards as he steps into a larger role with Drake London’s injury. His elevated status could turn him into a strategic FLEX option this week.

Keep these players on your radar as you make your waiver wire moves. The right additions can bring the championship closer to your grasp!